Full Schedule

7:00 AM – 5:00 PM

Registration Desk Open

Location: Registration Desk

7:30 AM – 5:00 PM

Systems Immunology Course (separate Registration Required)

Location: Salon F

Speaker: – Sanofi

Speaker: – Roche

Speaker: – Precision Medicine and Computational Biology, Sanofi US R&D

Speaker:

8:00 AM – 5:30 PM

Basic Immunology in Medicine Course (separate Registration Required)

Location: Salon G

Speaker: – Ragon Institute of MGH, Harvard and MIT, Cambridge, MA, USA

Speaker:

Sponsored By

7:00 AM – 5:00 PM

Registration Desk Open

Location: Registration Desk

7:30 AM – 12:00 PM

Big Data in Immunology Workshop

Location: Provincetown Room

Speaker: – University of California San Francisco

Speaker: – Boston University

Speaker:

7:30 AM – 5:45 PM

Cancer Immunity & Immunotherapy Course

Location: Gloucester Room, 3rd Floor

Co-Author: – Regeneron Therapeutics Inc

Co-Author: – Brigham and Women's Hospital

Speaker: – University of California, San Francisco

Speaker:

Speaker: – Massachusetts General Hospital, Broad Institute

Speaker:

Speaker: – Dana Farber Cancer Institute

Speaker:

8:00 AM – 9:30 AM

The Expanding Field of Inborn Errors of Immunity

Location: Salon C-D

Organized By

8:00 AM – 11:30 AM

Advances in Immunological Research: Impact on Healthcare

Location: Salon H-I

Organized By

8:00 AM – 11:30 AM

Latin-American Immunology Symposium

Location: Arlington Room, 3rd Floor

Organized By

8:00 AM – 12:00 PM

High Resolution Analysis of Target Organs and Cells to Reveal Local Inflammatory and Immune Mechanisms

Location: Salon A-B

Organized By

10:00 AM – 11:30 AM

Novel Crosstalk of Innate and Adaptive Immunity in Allergy and Asthma

Location: Salon C-D

Organized By

10:00 AM – 12:00 PM

Trans-omics Assessment in Clinical Immunology

Location: Salon J-K

Organized By

8:00 AM – 5:00 PM

The Microbiome and Immunity of Mast Cells and T Cells in Immunotherapy

Location: Virtual

Organized By

8:00 AM – 5:00 PM

Uncommon Inborn Errors of Immunity: An Egyptian Center Experience

Location: Virtual

Organized By

11:45 AM – 2:00 PM

FOCIS Centers of Excellence (FCE) Fusion: Careers. Collaboration. Connection. (Invitation Only)

Location: Berkeley to Fairfield Rooms, 3rd Floor

Sponsored By

1:30 PM – 3:00 PM

Cytokines in Barrier Immunity

Location: Salon C-D

Organized By

1:30 PM – 3:00 PM

Multi-omics Define a New Horizon in for Inflammatory Eye Diseases

Location: Salon J-K

Organized By

1:30 PM – 4:30 PM

Engineered T-cell Therapies to Treat Autoimmune Diseases and Restore Immune Tolerance

Location: Provincetown Room

Organized By

1:30 PM – 5:00 PM

Neuroimmune Interactions in Health and Disease

Location: Arlington Room, 3rd Floor

Organized By

1:30 PM – 5:30 PM

Immunometabolism 10 Years Later: Implications for Health and Disease and Translational Immunometabolism

Location: Salon H-I

Organized By

1:30 PM – 5:30 PM

Innovative Bioengineering Technologies and Strategies That Provide Mechanistic Insight and Guide Therapeutics in Cancer, Autoimmune Diseases and Transplant

Location: Salon A-B

Organized By

3:30 PM – 5:00 PM

Mucosal Immune Defenses in Health and Disease

Location: Salon C-D

Organized By

3:30 PM – 5:30 PM

Investigating Common Mechanisms of Autoimmunity

Location: Salon J-K

Organized By

6:00 PM – 7:45 PM

Opening Reception: Exhibits & Poster Presentations

Location: Salon E

Sponsored By

7:00 AM – 5:00 PM

Registration Desk Open

Location: Registration Desk

7:30 AM – 8:00 AM

Coffee with the Exhibitors

Location: Salon E

8:00 AM – 8:45 AM

Opening Keynote Address - Identification of RIOK2 as a Master Regulator of Human Blood Cell Development

Location: Salon F-G

Speaker: – Dana-Farber Cancer Institute

Chair: – Columbia University

8:45 AM – 9:35 AM

ImmunoOncology

Location: Salon F-G

Chair: – Brigham & Women's Hospital, Harvard Medical School, Broad Institute

Sponsored By

8:45 AM – 9:10 AM

Unleashing Inflammasome Activation to Control CD8+ T Cell Exhaustion in Cancer Immunotherapy

Location: Salon F-G

Speaker: – Institut Pasteur de Montevideo

9:10 AM – 9:35 AM

Mechanisms Driving CAR T Cells

Location: Salon F-G

Speaker: – Massachusetts General Hospital Cancer Center

9:35 AM – 10:00 AM

Coffee Break

Location: Salon E

10:00 AM – 11:30 AM

Engineered Car-cells in Oncology

Location: Salon F-G

Chair: – Graphite Bio

10:00 AM – 10:30 AM

Engineering the Fate and Function of T cell Therapies for Cancer

Location: Salon F-G

Presenter: – ArsenalBio

10:30 AM – 11:00 AM

CAR-T Toxicity: We Can Do Better

Location: Salon F-G

Presenter: – MGH Cancer Center

11:00 AM – 11:30 AM

Programming Smarter Cell Therapies

Location: Salon F-G

Presenter: – University of California, San Francisco

11:30 AM – 1:00 PM

Partner Program: Lupus Insight Prize Award Ceremony and Luncheon

Location: Gloucester Room, 3rd Floor

Speaker: – Chair, Lupus Research Alliance Scientific Advisory Board; Cornell University

Speaker: – The Francis Crick Institute

Speaker: – Drukier Institute for Children’s Health, Weill Cornell Medicine

Sponsored By

11:45 AM – 1:00 PM

Industrial Tutorial: Advances in Blood-based Profiling of Immune Response Biomarkers

Location: Provincetown Room

Speaker: – Stanford University

Speaker: – Alamar Biosciences

Sponsored By

11:45 AM – 1:00 PM

Industry Tutorial: Stimulation with a Superagonistic anti-cd28 Antibody Shows Treg Expansion and Provides an in Vitro Model for Immunotherapeutic Research with Biolegend

Location: Arlington Room, 3rd Floor

Speaker: – BioLegend Inc.

Sponsored By

1:00 PM – 2:45 PM

Neuroimmunology

Location: Salon F-G

Chair: – Benaroya Research Institute

Sponsored By

1:00 PM – 1:25 PM

The Immunopathogenesis of Narcolepsy Type 1

Location: Salon F-G

Speaker: – Toulouse University

1:25 PM – 1:40 PM

Proteogenomic Immune Signatures Delineate the Landscape of Pediatric Acquired Demyelinating Syndromes

Location: Salon F-G

Presenting Author: – University of Pennsylvania

1:40 PM – 2:05 PM

Control of CNS Inflammation by Engineered Probiotics

Location: Salon F-G

Presenter: – Brigham and Women's Hospital, Harvard University

2:05 PM – 2:20 PM

htlv-1-specific CD4+ T Cell Contribution to Neuroinflammation in htlv-1-associated Myelopathy

Location: Salon F-G

Presenting Author: – Imperial College London

Inflammatory Diseases

2:20 PM – 2:45 PM

Neuroimmunological Effects of Amyloid-β Immunization in the Human Brain and Meninges

Location: Salon F-G

Speaker: – Northwestern University

1:00 PM – 2:45 PM

Precision Diagnostics for Immune Disorders

Location: Salon A-D

Chair:

1:00 PM – 1:25 PM

Target Discovery Strategies for Developing Novel Cancer Immunotherapies

Location: Salon A-D

Speaker: – Indiana University

1:25 PM – 1:40 PM

TCR-MAP: A Novel, High-throughput T Cell Antigen Discovery Platform to Identify Viral- and Self-antigen TCR Reactivities in Rheumatoid Arthritis

Location: Salon A-D

Presenting Author: – Brigham and Women's Hospital & Harvard Medical School

1:40 PM – 2:05 PM

Discovering and Understanding Immune Archetypes in Cancer

Location: Salon A-D

Speaker: – University of California, San Francisco

2:05 PM – 2:20 PM

High-Dimensional Spectral Cytometry Panels for Whole Blood Immune Phenotyping in the Milieu Interieur 10-year Longitudinal Study

Location: Salon A-D

Presenting Author: – Institute Pasteur

2:20 PM – 2:45 PM

Clinical Development of Biomarkers in Immune-oncology: Strategies and Challenges

Location: Salon A-D

Speaker: – Compugen

1:00 PM – 2:45 PM

Tolerance Therapeutics

Location: Salon H-K

Chair: – Benaroya Research Institute / Immune Tolerance Network

Sponsored By

1:00 PM – 1:25 PM

IL-2 and Tregs in the Therapy of Autoimmune and Inflammatory Diseases

Location: Salon H-K

Speaker: – Sorbonne Université

1:25 PM – 1:40 PM

Pathophysiological Mechanisms and Molecular Indicators of IPEX Disease and Their Implications for the Development of New Therapies

Location: Salon H-K

Presenting Author: – Stanford University

Autoimmune Diseases

1:40 PM – 2:05 PM

Donor Negative Vaccine for Transplantation Tolerance

Location: Salon H-K

Speaker: – Duke University

2:05 PM – 2:20 PM

Blood TCR Signatures Classify Autoimmune Diseases and Predict Response to Low-dose IL-2

Location: Salon H-K

Presenting Author: – Sorbonne Université

Tolerance Therapeutics

2:20 PM – 2:45 PM

Re-programing Autoreactivity to Suppress Autoimmunity

Location: Salon H-K

Speaker: – University of Calgary

2:45 PM – 3:15 PM

Coffee Break

Location: Salon E

3:15 PM – 5:15 PM

Flow Cytometry Course: Day 1

Location: Provincetown Room

Chair: – Stanford University

Speaker: – Curiox Biosystems

Speaker: – Institute for Immunity, Transplantation, Infection - Stanford University

3:15 PM – 5:15 PM

Mechanisms of Autoimmunity

Location: Salon F-G

Chair: – Rouen Normandie University

3:15 PM – 3:30 PM

The Roles of CD4+ and CD8+ Regulatory T Cells in Controlling Autoimmune Response in the Human Tonsil Organoid System

Location: Salon F-G

Presenting Author: – Stanford University

Autoimmune Diseases

3:30 PM – 3:45 PM

Single Cell Sequencing Suggests Enteric Origins of Putative Pathogenic T Cells in hla-b27-associated Inflammation

Location: Salon F-G

Presenting Author: – Washington University School of Medicine

Autoimmune Diseases

3:45 PM – 4:00 PM

Opposing Effects of the Aryl Hydrocarbon Receptor and Type I Interferon Control Generation of CXCL13+ T Cells in Systemic Lupus Erythematosus

Location: Salon F-G

Presenting Author: – Brigham and Women's Hospital

4:00 PM – 4:15 PM

Improving Characterization of T-Cell Lineage and Activation States in scRNA-Seq with T-Cell AnnoTator (TCAT)

Location: Salon F-G

Presenting Author: – Brigham and Women's Hospital

Basic Science of Immunology - Adaptive Immunity

4:15 PM – 4:30 PM

Clonally Expanded T Cells Reveal a Pathophysiologic Distinction Between Disease Subtypes in Human Uveitis

Location: Salon F-G

Presenting Author: – Washington University in St. Louis

Inflammatory Diseases

4:30 PM – 4:45 PM

ALTB-268, a Tetravalent anti-psgl-1 Antibody Derived from ALTB-168, Shows Enhanced Potency in Treating T Cell Mediated Inflammatory Diseases

Location: Salon F-G

Presenting Author: – Altrubio Inc.

Inflammatory Diseases

4:45 PM – 5:00 PM

Pathogenic Autoreactive Th Cells Are Identified in Autoimmune Neuroinflammation by Expression of neuropilin-1 (NRP1)

Location: Salon F-G

Presenting Author: – National Institute of Neuroscience, NCNP

Autoimmune Diseases

5:00 PM – 5:15 PM

Investigation of T Cell-induced Neuroinflammation in Alzheimer’s Disease

Location: Salon F-G

Presenting Author: – Columbia University

Inflammatory Diseases

3:15 PM – 5:30 PM

Immunooncology and Cell Therapy

Location: Salon A-D

Chair: – Emory University

Sponsored By

3:15 PM – 3:30 PM

CART-cell Therapy Directed Towards Novel CD84 Antigen for the Treatment of Acute Myeloid Leukemia

Location: Salon A-D

Presenting Author: – Hospital Clinic de Barcelona

Immuno-engineering and Cellular Therapies

3:30 PM – 3:45 PM

Removal of Endogenous TCR Chains for Tcr-based Immunotherapies

Location: Salon A-D

Presenting Author: – Columbia University

Immuno-oncology

3:45 PM – 4:00 PM

Unique Cellular and Autoantibody Signatures in Patients with Iraes Revealed by Longitudinal Immune Tracking

Location: Salon A-D

Presenting Author: – University of Pennsylvania

Autoimmune Diseases

4:00 PM – 4:15 PM

CRISPR/Cas9-Based Editing of KLRC1 Enhances the Efficacy of Primary CD33-Targeting CAR-NK Cells Against Acute Myeloid Leukemia

Location: Salon A-D

Presenting Author: – Goethe University Frankfurt

Immuno-engineering and Cellular Therapies

4:15 PM – 4:30 PM

FOXp3+ Regulatory T Cells Co-localize with CD8+ T Cells in Tumors Responding to PD-1 Blockade

Location: Salon A-D

Presenting Author: – McGill University

Immuno-oncology

4:30 PM – 4:45 PM

Local and Systemic Immune Response Against Tumor Specific and Tumor-associated Antigens in Patients with Localized Uveal Melanoma (UM)

Location: Salon A-D

Presenting Author: – Institut Curie

Immuno-oncology

4:45 PM – 5:00 PM

Immuno-stat Platform: Tcr-selective Engagers for Selective Targeting of IL-2 to Tumor-specific T Cells

Location: Salon A-D

Presenting Author: – Cue Biopharma

Immuno-oncology

5:00 PM – 5:15 PM

Selective Depletion of Follicular Helper T Cells Using Chimeric Antigen Receptor Natural Killer Cells

Location: Salon A-D

Presenting Author: – Cincinnati Children's Hospital Medical Center

Immuno-engineering and Cellular Therapies

5:15 PM – 5:30 PM

Antibodies to PODXL as an Approach to Targeting Tumor Stem Cells

Location: Salon A-D

Presenting Author: – University of British Columbia

Immuno-oncology

3:15 PM – 5:30 PM

Late-Breaking Abstracts

Location: Salon H-K

Chair: – Journal of Experimental Medicine (JEM)

3:15 PM – 3:30 PM

Activating the cGAS/STING Pathway Suppresses Regulatory T Cell Function and Induces Antiviral Interferon Secretion in a Temperature-Sensitive Manner.

Location: Salon H-K

Presenting Author: – Vanderbilt University

Basic Science of Immunology - Adaptive Immunity

3:30 PM – 3:45 PM

An Acquired Error of Immunity with high frequency somatic mutations in STAT5B and KRAS.

Location: Salon H-K

Presenting Author: – Garvan Institute of Medical Research

Immunogenetics

3:45 PM – 4:00 PM

Dermatomyositis skin inflammation is associated with type-I IFN response and the presence of PD1-high, CXCR5-, CXCL13+ CD4+ T cells, which expands in response to UVB irradiation

Location: Salon H-K

Presenting Author: – UMass Chan Medical School

Autoimmune Diseases

4:00 PM – 4:15 PM

Mapping Human Thymic Regulatory T Cell Development Using Spatial Multiomics

Location: Salon H-K

Presenting Author: – BC Children's Hospital Research Institute, University of British Columbia

Basic Science of Immunology - Adaptive Immunity

4:15 PM – 4:30 PM

Natural killer cells as immunological signatures of long-term stable remission in Rheumatoid Arthritis

Location: Salon H-K

Presenting Author: – King's College London

Autoimmune Diseases

4:30 PM – 4:45 PM

Serum- and Feeder-Free Generation of CD4 Single Positive T Cells and Regulatory T Cells from Human Induced Pluripotent Stem Cells

Location: Salon H-K

Presenting Author: – Sangamo Therapeutics

Immuno-engineering and Cellular Therapies

4:45 PM – 5:00 PM

The cation channel TMEM176B as a protective factor in autoimmune encephalomyelitis

Location: Salon H-K

Presenting Author: – Institut Pasteur Montevideo

5:00 PM – 5:15 PM

On The Clonal Evolution Of Pathogenic And Non-pathogenic Donor-specific B Cell Responses To Kidney Transplantation In Human Recipients

Location: Salon H-K

Presenting Author: – University of Michigan

5:30 PM – 6:15 PM

Keynote Address - Translating Immunology into New Therapies for Inflammatory Bowel Disease

Location: Salon F-G

Speaker: – University of Oxford

Chair: – Nantes Université, CHU Nantes, INSERM, Center for Research in Transplantation and Translational Immunology, UMR 1064, ITUN, F-44000, Nantes, France

Sponsored By

6:15 PM – 7:30 PM

Exhibits & Poster Presentations Reception

Location: Salon E

7:30 PM – 8:30 PM

FOCIS Member Reception (FOCIS members only)

Location: 3rd Floor Atrium

Sponsored By

7:00 AM – 5:00 PM

Registration Desk Open

Location: Registration Desk

7:30 AM – 8:00 AM

Coffee with the Exhibitors

Location: Salon E

7:30 AM – 7:45 PM

Exhibition & Poster Hall Open (authors optional)

Location: Salon E

8:00 AM – 9:30 AM

Fibrosis and Wound Healing

Location: Salon F-G

Chair: – Yale School of Medicine

8:00 AM – 8:30 AM

Lung Fibroblast Heterogeneity in Health and Disease

Location: Salon F-G

Speaker: – University of California, San Francisco

8:30 AM – 9:00 AM

Title TBD

Location: Salon F-G

Speaker: – Regeneron

9:00 AM – 9:30 AM

Advances, Challenges, and New Therapeutic Strategies for Fibrotic Disease

Location: Salon F-G

Speaker: – Pfizer, Inc.

9:35 AM – 10:00 AM

Coffee Break

Location: Salon E

10:00 AM – 10:30 AM

Metabolic Causes and Consequences of Post-viral Syndromes

Location: Salon F-G

Speaker: – University of Pennsylvania

10:30 AM – 11:00 AM

TBD

Location: Salon F-G

Speaker: – Stanford University

11:00 AM – 11:30 AM

Viral Persistence, Immune Dysregulation and Inflammation Following COVID-19 - A New Paradigm?

Location: Salon F-G

Speaker: – University of California, San Francisco

11:30 AM – 1:00 PM

Partner Program: History of Women in FOCIS: Navigating Your Way into a Leadership Role

Location: Gloucester Room, 3rd Floor

Speaker: – Stanford University

Co-Chair: – UCLA

Co-Chair: – University of Pennsylvania

Co-Chair: – University of British Columbia

Sponsored By

1:00 PM – 2:45 PM

Disorders of Innate Immunity

Location: Salon A-D

Chair: – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), San Raffaele Scientific Institute

1:00 PM – 1:25 PM

Role of Functional Programming of Alveolar Macrophages in the Susceptibility to Pneumonia and Cancer After Acute Inflammation

Location: Salon A-D

Speaker: – Nantes University

1:25 PM – 1:40 PM

Establishing Leptomeninges Immune Dynamics and Regulatory Control of T Cell Infiltration in the Degenerating Human Brain

Location: Salon A-D

Presenting Author: – Columbia University

Disorders of Innate Immunity

1:40 PM – 2:05 PM

Inborn Errors of Pattern-triggered Immunity

Location: Salon A-D

Speaker: – Ludwig-Maximilians-University of Munich

2:05 PM – 2:20 PM

Virus Infection Causes Intestinal Dysbiosis to Promote Type 1 Diabetes Development

Location: Salon A-D

Presenting Author: – University of British Columbia

Disorders of Innate Immunity

2:20 PM – 2:45 PM

The Two Faces of Autoinflammatory Skin Disorders

Location: Salon A-D

Speaker: – University of California, San Diego

1:00 PM – 2:45 PM

Engineered Cell Therapy - Non-oncology

Location: Salon F-G

Chair:

1:00 PM – 1:25 PM

Enhancing Engineered Treg Therapies

Location: Salon F-G

Speaker: – Sonoma Biotherapeutics

1:25 PM – 1:40 PM

Crispr-mediated Deletion of PD1 to Enhance the Efficacy of Human CAR Tregs

Location: Salon F-G

Presenting Author: – The University of British Columbia

Engineered Cell Therapy - Non-Oncology

1:40 PM – 2:05 PM

Engineering Tcr-tregs for Autoimmune Disease

Location: Salon F-G

Speaker: – Abata Therapeutics

2:05 PM – 2:20 PM

GNTI-122 Is a Stable Engineered Regulatory T Cell Therapy for Type 1 Diabetes That Is Specific, Expandable, and Efficacious in in Vivo Models

Location: Salon F-G

Presenting Author: – GentiBio, Inc

Engineered Cell Therapy - Non-Oncology

2:20 PM – 2:45 PM

Rescuing Primary Immundeficiencies by Advanced Genetic Engineering of Hematopoietic Stem Cells and T cells

Location: Salon F-G

Speaker: – San Raffaele Telethon Institute for Gene Therapy (SR-Tiget)

1:00 PM – 2:45 PM

Microbiome/Mucosal Immunity

Location: Salon H-K

Chair: – Instituto de Biotecnologia/ UNAM & MEXTIRG FCE

1:00 PM – 1:25 PM

Unveiling the Complexity of IgE and Food Allergy: Beyond Clinical Reactions

Location: Salon H-K

Speaker: – King's College London

1:25 PM – 1:40 PM

Molecular Underpinnings and Significance of Regulatory T-cell Plasticity in Cancer

Location: Salon H-K

Presenting Author: – Mayo Clinic

Microbiome / Mucosal Immunity

1:40 PM – 2:05 PM

Small Intestinal Tuft Cells: Sentinels and Effectors of Type 2 Immunity

Location: Salon H-K

Speaker: – University of Washington

2:05 PM – 2:20 PM

Mapping the Impact of Vaccination and Viral Strain on sars-cov-2 Infection and Host Response in the Human Nasal Mucosa

Location: Salon H-K

Presenting Author: – Harvard Medical School / Boston Children's Hospital

Microbiome / Mucosal Immunity

2:20 PM – 2:45 PM

Extracellular Vesicles Isolated from Prevotella Histicola Induce a Population of Inflammation Resolving CD4 T Cells

Location: Salon H-K

Speaker: – Evelo Biosciences

2:45 PM – 3:15 PM

Coffee Break

Location: Salon E

3:15 PM – 5:15 PM

COVID and Infectious Diseases

Location: Salon A-D

Chair:

3:15 PM – 3:30 PM

Similarities and Differences Between Myocarditis Following COVID-19 Mrna Vaccine and Multiple Inflammatory Syndrome with Cardiac Involvement in Children

Location: Salon A-D

Presenting Author: – Bambino Gesù Children's Hospital

COVID-19

3:30 PM – 3:45 PM

3rd and 4th Doses of Mrna Vaccines Broaden and Prolong Immune Responses to sars-cov-2 in Immunocompromised Patients with Immune-mediated Inflammatory Diseases

Location: Salon A-D

Presenting Author: – University of Toronto

COVID-19

3:45 PM – 4:00 PM

Longitudinal Antigen-specific Immune Profiling During sars-cov-2 Breakthrough Infection Highlights Early Activation of Memory CD8 T Cells Followed by Later Activation of Memory B Cells

Location: Salon A-D

Presenting Author: – University of Pennsylvania

COVID-19

4:00 PM – 4:15 PM

Heme Oxygenase 1 (HO-1) Expression in Dendritic Cells Promotes Antiviral Immunity Against Herpes Simplex Virus Skin Infection

Location: Salon A-D

Presenting Author: – P. Universidad Católica de Chile

Infectious Diseases

4:15 PM – 4:30 PM

Characterization of novel Nematode Pan Allergen (NPA)

Location: Salon A-D

Presenting Author: – University of Illinois Chicago, College of Medicine Rockford

4:45 PM – 5:00 PM

Effects of Latent EBV on Responses to anti-cd3 Mab (teplizumab) in Type 1 Diabetes

Location: Salon A-D

Presenting Author: – Yale University

Autoimmune Diseases

5:00 PM – 5:15 PM

Serological Assessment of Patients Undergoing Peanut Oral Immunotherapy: The Role of IgG4

Location: Salon A-D

Presenting Author: – McGill University

3:15 PM – 5:15 PM

Flow Cytometry Course: Day 2

Location: Provincetown Room

Chair: – Stanford University

Speaker: – Stanford University

Speaker: – Icahn School of Medicine at Mount Sinai

3:15 PM – 5:15 PM

Immunogenetics

Location: Salon H-K

Chair: – Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics and Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine

3:15 PM – 3:30 PM

Genetic Variants Associated with Immune Cell Population Abundances in Single-cell Data

Location: Salon H-K

Presenting Author: – Harvard University

Autoimmune Diseases

3:30 PM – 3:45 PM

Chromatin Conformation During CD4+ T Cell Activation Implicates Autoimmune Disease Candidate Genes

Location: Salon H-K

Presenting Author: – The Children's Hospital of Philadelphia

Immunogenetics

3:45 PM – 4:00 PM

The FAM72 Gene Family Promotes Cancer Development by Disabling the Base Excision Repair System

Location: Salon H-K

Presenting Author: – University of Toronto

Immuno-oncology

4:00 PM – 4:15 PM

Leveraging Single Cell Transcriptomics to Identify Pathogenic Cell Lineages

Location: Salon H-K

Presenting Author: – Precision Medicine and Computational Biology, Sanofi US R&D

Autoimmune Diseases

4:15 PM – 4:30 PM

Overactive STAT3 Drives Dysregulated Accumulation of Self-reactive and Autoimmune-associated cd21low cd23low B Cells

Location: Salon H-K

Presenting Author: – Garvan Institute of Medical Research

Immunogenetics

4:30 PM – 4:45 PM

Genome-wide Crispr-interference Screens Connect Non-coding Autoimmune Risk Variants to T Cell Functions

Location: Salon H-K

Presenting Author: – Benaroya Research Institute

Immunogenetics

4:45 PM – 5:00 PM

Role of fam83h in Immune System Homeostasis

Location: Salon H-K

Presenting Author: – Institute of Molecular Genetics of the Czech Academy of Sciences

Autoimmune Diseases

5:00 PM – 5:15 PM

Integrative Functional Genomics Points to Natural Killer Cells as Key Drivers in Pathogenesis of Ankylosing Spondylitis

Location: Salon H-K

Presenting Author: – Boston Children's Hospital

3:15 PM – 5:30 PM

Allergy and Autoantigens

Location: Salon F-G

Chair: – Brigham and Women's Hospital

3:15 PM – 3:30 PM

A Search for Post-translationally-modified Trichohyalin Epitopes: Potential Triggers of Autoimmunity to Hair Follicles in Alopecia Areata

Location: Salon F-G

Presenting Author: – University College Dublin, Belfield, Dublin, Ireland

Autoimmune Diseases

3:30 PM – 3:45 PM

A Biosensor of Immunologic Synapse Formation for Multiplexed T Cell Antigen Discovery

Location: Salon F-G

Presenting Author: – University of California, San Francisco

Immuno-engineering and Cellular Therapies

3:45 PM – 4:00 PM

Transforming Growth factor-β3 Maintains Intestinal Tolerance

Location: Salon F-G

Presenting Author: – UT Southwestern

Mucosal Immunology

4:00 PM – 4:15 PM

interleukin-4 Activates Olfactory Sensory Neurons and Induces Loss of Smell in Mice Through Distinct Molecular Signatures

Location: Salon F-G

Presenting Author: – Sanofi

Inflammatory Diseases

4:15 PM – 4:30 PM

Deep Immunophenotyping Reveals Cellular Phenotypes in Peripheral Blood Associated with Specific Patterns of Kidney Injury in Lupus Nephritis

Location: Salon F-G

Presenting Author: – Brigham and Woman's Hospital

Autoimmune Diseases

4:30 PM – 4:45 PM

Correlation of Urine Immune Cells with Renal Histological Features in Lupus Nephritis: Lessons from the Accelerating Medicines Partnership (AMP) in SLE Consortium

Location: Salon F-G

Presenting Author: – University of Washington

Autoimmune Diseases

4:45 PM – 5:00 PM

Sialic Acids on House Dust Mite (HDM) Allergen, Der P 2, Shift Immune Responses Towards a Regulatory Profile

Location: Salon F-G

Presenting Author: – Amsterdam University Medical Center

Allergy

5:00 PM – 5:15 PM

Understanding the Plausible Implications of Dysregulated Interferon Signaling on Esophageal Epithelial Cell Function

Location: Salon F-G

Presenting Author: – Children's Hospital of Philadelphia

Allergy

5:15 PM – 5:30 PM

Rhinovirus Infected Epithelial Cells Drive Genetic Susceptibility to Childhood-Onset Asthma

Location: Salon F-G

Presenting Author: – Boston Children's Hospital

Allergy

5:30 PM – 5:40 PM

State of FOCIS

Location: Salon F-G

Speaker: – Columbia University

5:40 PM – 6:25 PM

Keynote Address - CAR T cells for Oncology and Beyond

Location: Salon F-G

Speaker: – University of Pennsylvania

Chair: – Graphite Bio

6:30 PM – 7:45 PM

Exhibits & Poster Presentations Reception

Location: Salon E

Sponsored By:

7:00 AM – 3:45 PM

Registration Desk Open

Location: Registration Desk

8:00 AM – 9:30 AM

Adaptive/Autoimmunity

Location: Salon F-G

Chair: – Seismic Therapeutic

Sponsored By

8:00 AM – 8:30 AM

CD8 T cell derived granzyme K drives a new pathway of complement activation in inflamed tissues

Location: Salon F-G

Speaker: – Brigham and Women's Hospital, Harvard Medical School

8:30 AM – 9:00 AM

Epigenetic Control of IL-9 in Inflammatory Disease: Lessons Learned from a Patient-driven Approach

Location: Salon F-G

Speaker: – University of Pittsburgh

9:00 AM – 9:30 AM

Dissecting Regulatory T Cells in Autoimmune Type 1 Diabetes

Location: Salon F-G

Speaker: – Helmholtz Center Munich & LMU Munich

9:30 AM – 10:00 AM

Coffee Break

Location: Salon E

10:00 AM – 11:30 AM

Atopic Diseases: Allergy/type 2/helminth

Location: Salon F-G

Chair: – Columbia University

Sponsored By

10:00 AM – 10:30 AM

Allergen Recognition by Nasal Microvillous Tuft Cells Directs Stem Cell Activation and Type 2 Inflammation

Location: Salon F-G

Speaker: – Brigham and Women's Hospital/Harvard Medical School

10:30 AM – 11:00 AM

Human Single Gene Defects That Cause Severe Atopic Disease: A Focus on STAT6 Gain-of-function

Location: Salon F-G

Speaker: – University of British Columbia / BC Children's Hospital

11:00 AM – 11:30 AM

Trust your gut? Food allergy and the microbiome

Location: Salon F-G

Speaker: – Icahn School of Medicine at Mount Sinai

11:45 AM – 12:30 PM

Keynote Address - Spatial Organization of the Immune Response in Tumors

Location: Salon F-G

Speaker: – The Broad Institute

Chair: – Columbia University

12:30 PM – 2:00 PM

Partner Program: Journal of Experimental Medicine – Meet the Editor

Location: Arlington Room, 3rd Floor

Presenter: – Journal of Experimental Medicine (JEM)

Sponsored By

12:45 PM – 2:00 PM

Partner Program: Getting Your Application Off on the Right Foot: Receipt and Referral

Location: Provincetown Room

Speaker: – DAIT/NIAID/NIH/DHHS

Speaker: – NIAID/NIH

Sponsored By

2:00 PM – 3:45 PM

Cutting Edge of Transplantation

Location: Salon F-G

Chair: – University of Oxford

2:00 PM – 2:25 PM

Heterogeneity and Plasticity of Alloreactive T cell Clones in a Human Non-lymphoid Tissue

Location: Salon F-G

Speaker: – Columbia University Medical Center

Cutting Edge of Transplantation

2:25 PM – 2:40 PM

Single Cell Transcriptomic Analysis of Renal Allograft Rejection Reveals Novel Insights into Intra-graft TCR Clonality and Rejection Mechanisms

Location: Salon F-G

Presenting Author: – Cincinnati Children's Hospital Medical Center

Cutting Edge of Transplantation

2:40 PM – 3:05 PM

What Is Next in Xenotransplantation

Location: Salon F-G

Speaker: – University of Maryland School of Medicine

3:05 PM – 3:20 PM

Dynamic Establishment of Recipient Resident Memory T Cell Repertoire After Human Intestinal Transplantation

Location: Salon F-G

Presenter: – Columbia University

Cutting Edge of Transplantation

3:20 PM – 3:45 PM

Paradoxical Effects of Prior Pregnancy on Subsequent Transplantation

Location: Salon F-G

Speaker: – The University of Chicago

2:00 PM – 3:45 PM

Disorders of Humoral Immunity

Location: Salon A-D

Sponsored By

2:00 PM – 2:25 PM

Nucleic Acid Sensing Disorders and Human Autoimmunity

Location: Salon A-D

Speaker: – The Francis Crick Institute

2:25 PM – 2:40 PM

EBV in Multiple Sclerosis: Molecular Mimicry Between EBV EBNA1 and Glialcam

Location: Salon A-D

Presenting Author: – Stanford University

Disorders of Humoral Immunity

2:40 PM – 3:05 PM

Complexity of the Immune Response to sars-cov-2: From Molecules to Cells and Return

Location: Salon A-D

Speaker: – University of Modena and Reggio Emilia

3:05 PM – 3:20 PM

Molecular and Cellular Dissection of the Nephrotic B-cell Response Reveals a Prominent Atypical B-cell Signature in Relapses of Idiopathic Nephrotic Syndrome

Location: Salon A-D

Presenting Author: – McGill University

Disorders of Humoral Immunity

3:20 PM – 3:45 PM

B Cell Abnormalities in Systemic Lupus Erythematosus

Location: Salon A-D

Speaker: – Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo

2:00 PM – 3:45 PM

Immunity Across the Ages

Location: Salon H-K

Chair: – Sorbonne Université

2:00 PM – 2:25 PM

Title TBD

Location: Salon H-K

Speaker: – Genentech

2:25 PM – 2:40 PM

A Rheostat Governs Maturation and Regulation of in Utero Human Fetal T Cells

Location: Salon H-K

Presenting Author: – Translational Immunology Institute/Singapore Health Services Pte Ltd (Singhealth)

Immunology Across the Ages

2:40 PM – 3:05 PM

New Strategies to Rejuvenate Immunity

Location: Salon H-K

Speaker: – Sentcell LTD

3:05 PM – 3:20 PM

Dynamic Circulating T Cell Activation States in Extremely Premature Infants

Location: Salon H-K

Presenting Author: – Yale University School of Medicine

Immunity Across the Ages

3:20 PM – 3:45 PM

Senescent Immune Cells vs. Immunosenescence

Location: Salon H-K

Speaker: – University of Minnesota

8:00 AM – 11:30 AM

Crosstalk between stress and immunity