Session: Atopic Diseases: Allergy/Type 2/Helminth

Human Single Gene Defects That Cause Severe Atopic Disease: A Focus on STAT6 Gain-of-function

Friday, June 23, 2023

10:30 AM – 11:00 AM

Location: Salon F-G

Speaker(s)

Stuart Turvey, MBBS, DPhil, FRCPC

Professor
University of British Columbia / BC Children's Hospital
Vancouver, British Columbia, Canada

Disclosure(s):

Stuart Turvey, MBBS, DPhil, FRCPC: No financial relationships to disclose

Appreciate that single gene defects can casue severe allergic disease in humans.
Recognize key features suggestive of a monogenic primary atopic disorder.
Understand how gain-of-function variants in STAT6 cause severe, early-onset allergic disease in humans.