E.F. Brigham Professor of Medicine Brigham and Women's Hospital, Harvard Medical School Newton, Massachusetts, United States
Disclosure(s):
Michael Brenner, MD: 4FOX Ventures: Consultant/Advisor (Ongoing); GSK: Consultant/Advisor (Ongoing); Mestag Therapeutics: Equity/Owner (Ongoing); Ono Pharmaceuticals: Consultant/Advisor (Ongoing); Third Rock Ventures: Consultant/Advisor (Ongoing)
Learning Objectives:
Upon completion, participant will recognize granzyme K+ T cells as the major CD8 T cell population expanded in inflamed tissue in RA, UC, CD and other inflamed tissues.
Participants will learn about a new pathway of complement activation and the key role of granzyme K in initiating it.
Participants will learn about the subsets of CD8+ T cells in human autoimmune tissues