Mechanisms of Autoimmunity

Chair(s)

• OB

  Olivier Boyer, M.D., Ph.D.

  Rouen Normandie University
  Rouen, Haute-Normandie, France

Presentations:

• 3:15 PM – 3:30 PM  

  The Roles of CD4+ and CD8+ Regulatory T Cells in Controlling Autoimmune Response in the Human Tonsil Organoid System
  

  Presenting Author: Xin Chen – Stanford University
• 3:30 PM – 3:45 PM  

  Single Cell Sequencing Suggests Enteric Origins of Putative Pathogenic T Cells in hla-b27-associated Inflammation
  

  Presenting Author: Michael A. Paley, MD PhD – Washington University School of Medicine
• 3:45 PM – 4:00 PM  

  Opposing Effects of the Aryl Hydrocarbon Receptor and Type I Interferon Control Generation of CXCL13+ T Cells in Systemic Lupus Erythematosus
  

  Presenting Author: Vanessa Sue Wacleche – Brigham and Women's Hospital
• 4:00 PM – 4:15 PM  

  Improving Characterization of T-Cell Lineage and Activation States in scRNA-Seq with T-Cell AnnoTator (TCAT)
  

  Presenting Author: Dylan Kotliar, MD PhD – Brigham and Women's Hospital
• 4:15 PM – 4:30 PM  

  Clonally Expanded T Cells Reveal a Pathophysiologic Distinction Between Disease Subtypes in Human Uveitis
  

  Presenting Author: Lynn M. Hassman, MD. PhD – Washington University in St. Louis
• 4:30 PM – 4:45 PM  

  ALTB-268, a Tetravalent anti-psgl-1 Antibody Derived from ALTB-168, Shows Enhanced Potency in Treating T Cell Mediated Inflammatory Diseases
  

  Presenting Author: Yu-Chin Lin, MS – Altrubio Inc.
• 4:45 PM – 5:00 PM  

  Pathogenic Autoreactive Th Cells Are Identified in Autoimmune Neuroinflammation by Expression of neuropilin-1 (NRP1)
  

  Presenting Author: Ben JE Raveney, Ph.D. – National Institute of Neuroscience, NCNP
• 5:00 PM – 5:15 PM  

  Investigation of T Cell-induced Neuroinflammation in Alzheimer’s Disease
  

  Presenting Author: Yiran Cheng, MSc – Columbia University