Immunometabolism 10 Years Later: Implications for Health and Disease and Translational Immunometabolism
Tuesday, June 20, 2023
1:30 PM – 5:30 PM
Location: Salon H-I
Organized By
Immunity and metabolism can reciprocally influence each other. It is now clear that interactions between the immune system and both systemic and cellular metabolism are key factors for the activation of immune cells and the regulation of inflammation and that the deregulation of these interactions is associated with multiple human disorders.
The field of immunometabolism has thrived over the last decade, revealing major roles played by immune cells in metabolic homeostasis and the functional impact of metabolic pathways on immune cell function. As new discoveries continue to reveal the tangled links between immunology and metabolism, scientists have also been working to understand how to exploit this accumulated knowledge and translate it into novel therapies for human diseases.
This Symposium will cover the latest advances in immunometabolism presented by Canadian leaders in the field. Moreover, it will also focus on emerging technologies to study such systems and to identify novel molecular targets to treat human diseases.
Organizing Society Canadian Society for Immunology
Session Chairs Francesca Di Cara Ramon Klein Geltink
Session Agenda 1:30 PM - 2:00 PM Uncovering Novel Metabolic Insights in T cells with 13C-glucose Tracing in Human Ovarian Cancer Julian Lum University of Victoria
2:00 PM - 2:30 PM Insulin Receptor Signaling in Adaptive Immunity Sue Tsai University of Alberta
2:30 PM - 3:00 PM PI 3-kinase-dependant Reprogramming of Hexokinase Isoforms Regulates B cell Metabolism and Function Aaron Marshall University of Manitoba
3:00 PM - 3:30 PM Break
3:30 PM - 4:00 PM PM Mitochondrial Complex III ROS Improves Anti-tumor CD8+ T cell Function Ramon Klein Geltink University of British Columbia
4:00 PM - 4:30 PM Peroxisome’s Metabolism Orchestrates Myeloid Cells Development and Activation in Health and Disease Francesca Di Cara Dalhousie University
4:30 PM - 5:00 PM Nutrient and Energy-sensing Pathways as Drivers of Macrophage Immunometabolism Morgan Fullerton University of Ottawa