Until recently, the immune and the nervous systems were thought to operate independently. Recent findings, however, have challenged this view, revealing important neuroimmune interactions that operate in health and disease. Moreover, it was recently shown to these neuroimmune interactions are controlled by the commensal microbiome, via the production of microbial metabolites or the activation of complex biologic responses. In this Symposium, we propose to bring together leading neuroimmunologists to discuss the mechanisms that participate in the cross-talk between the immune and the nervous system, focusing on specific cell subsets, molecular pathways and microbiome components which play important roles in development, homeostasis and disease. In summary, this symposium will highlight the important roles played by neuroimmune interactions in health and disease, as well as potential approaches for their therapeutic modulation.
Organizing Society International Society of Neuroimmunology
Session Chair Francisco Quintana
Session Agenda 1:30 PM - 2:15 PM Neuroimmune Interactions in Regulation of Immunity Vijay K Kuchroo Harvard Medical School
2:15 PM - 3:00 PM Enteric Nervous System Regulation of Innate Immunity Meenakshi Rao Harvard Medical School
3:00 PM - 3:30 PM Break
3:30 PM - 4:15 PM Bacteria Hijack Pain and a Neuroimmune Axis to Facilitate Brain Invasion Isaac Chiu Harvard Medical School
4:15 PM - 5:00 PM Regulatory Cell-cell Interactions in CNS Inflammation Francisco J Quintana Harvard Medical School