High Resolution Analysis of Target Organs and Cells to Reveal Local Inflammatory and Immune Mechanisms
Tuesday, June 20, 2023
8:00 AM – 12:00 PM
Location: Salon A-B
Organized By
The symposium will present single cell high resolution and spatial 'omics for immune cells stimulated by alloantigen or other inflammatory events. Technical and informatics analyses will be highlighted along with the implications of data outputs for understanding mechanisms and devising therapeutic interventions.
Organizing Societies American Society for Histocompatibility and Immunogenetics (ASHI) The Transplantation Society (TTS) The American Society of Transplantation (AST)
8:10 AM - 8:45 AM Spatial Imaging in Mouse Kidney Transplant Rejection Martin Oberbarnscheidt, MD, PhD University of Pittsburgh
8:45 AM - 9:20 AM Spatial Transcriptomics in COVID Patients Fadi Issa, MD, PhD University of Oxford
9:20 AM - 9:55 AM Multi-Omic Assessment of Allograft Rejection in Kidney Transplantation Steve Woodle, MD, PhD Cincinnati Children's Hospital Medical Center
9:55 AM - 10:10AM Break
10:10 AM - 10:45 AM Dynamic Changes to Tissue-resident Immunity After MHC-matched and MHC-mismatched Solid Organ Transplantation Michaela Lucas, PhD University of Western Australia
10:45 AM - 11:20 AM Single-cell Profiling of Healthy Human Kidney Reveals Features of Sex-based Transcriptional Programs and Tissue Specific Immunity Ana Konvalinka, BSc, MD, PhD University Health Network Toronto
11:20 AM - 11:55 AM Spatial Transcriptomics in Human Kidney Transplants Paolo Cravedi, MD, PhD Icahn School of Medicine at Mount Sinai