Multi-omics Define a New Horizon in for Inflammatory Eye Diseases
Tuesday, June 20, 2023
1:30 PM – 3:00 PM
Location: Salon J-K
Organized By
Uveitis is a heterogeneous group of inflammatory eye diseases for which pathophysiologic mechanisms are poorly understood, presenting a significant barrier to highly effective therapy.
In recent years, new molecular analysis techniques have advanced our ability to study how interactions between genetic variants, protein expression and the environment lead to disease phenotypes. Multi-omics, or the integrated analysis of large datasets encompassing genomic, proteomic, transcriptomic, metabolomic, and microbiome analyses, has the potential to provide an unprecedented level of pathophysiologic insight into inflammatory diseases. This, in turn, should lead to improved classification of disease subtypes along with identification of disease-specific therapeutic targets.
This symposium will bring together experts from different subspecialties to catalyze advancements in the application of multi-omic analyses towards improved classification and understanding of ocular inflammatory diseases.
2:20 PM - 2:35 PM Peripheral Selection of T cell Antigen Receptors Mimics Thymic Positive Selection Kaitlyn Lagattuta, BS Harvard Medical School
2:35 PM - 2:50 PM Integrative Multi-Omic Analysis Sheds New Light on the Pathogenesis of Vogt-Koyanagi-Harada Disease Qingfeng Wang, MD Chongqing Medical University
2:50 PM - 3:00 PM Closing Discussion & Questions for the Panel