Research Engineer
Institut Curie, France
Ana Ines Lalanne, PhD, Laboratoire d'Immunologie Clinique, Institut Curie, Paris, France.
Born in Montevideo, Uruguay in 1974, she studied biochemistry at the Faculty of Sciences, and obtained a Master's degree in molecular and cell biology. She then moved to France and continued her studies at the Institut Pasteur in Paris, where she completed her PhD in immunology on B cell development in mice. During her postdoctoral research in the same institute, she investigated the interaction between microbiota and inflammation.
Interested in research on human diseases, she worked for two years at the Institut Cochin, where she investigated the role of self-reactive T cells in type-1 diabetes. Currently, she works at the Institut Curie in Paris, which consists of a cancer specialized hospital and a research center. She is a research engineer in the Clinical Immunology lab, headed by Dr. Lantz. She works at the interface between clinics and research, and is responsible for immune monitoring of patients participating in clinical trials, particularly those receiving different types of immunotherapies.
Her work focuses on two main subjects. The first is anti-tumor immune responses in patients with uveal melanoma. Her team discovered a new class of neo-epitopes generated by mutated forms of the SF3B1 splicing factor. Her other area of interest is immune responses against anti-tumor therapeutic vaccines, either targeting conserved epitopes like HPV or individual mutations, such as in the case of personalized vaccines.
