Professor
Brigham and Women's Hospital
Stephen Elledge is the Gregor Mendel Professor of Genetics and Medicine in the Department of Genetics at Harvard Medical School and the Department of Medicine at Brigham and Women’s Hospital and is an Investigator with Howard Hughes Medical Institute. He received his Ph.D. in Biology from MIT in 1983 where he worked with Dr. Graham Walker and isolated the genes for the first translesion DNA polymerase, UmuCD. He performed post-doctoral studies in the Department of Biochemistry at Stanford University where he discovered a replication stress response pathway now known as the DNA damage response. He joined the faculty of Baylor College of Medicine in 1989 in the Department of Biochemistry until moving to Harvard Medical School in 2003 where he developed genetic technologies applied to human immunology, the DNA damage response and the understanding of protein stability.
He was awarded the American Association of Cancer Research G.H.A. Clowes Memorial Award in 2001, Paul Mark’s Prize in Cancer Research in 2001, and the National Academy of Sciences Award in Molecular Biology in 2002. He was awarded the Genetics Society of America Medal and the Hans Sigrist International Prize in 2005. In 2006 he was elected to the National Academy of Medicine. He received the Gairdner Foundation International Award in 2013. He was the 2015 recipient of the Wiley Prize and the Albert Lasker Prize in basic Medicine. In 2016, he received the Breakthrough Prize in Life Sciences.
