PRESIDENT ENDOCRINE TECHNOLOGY, LLC NY, New York, United States
Abstract Text: The Problem: Complement-mediated inflammation is a contributor to the dysfunction in lipid metabolism. This is associated with the pathogenesis of aging involving different diseases such as Age related macular degeneration (AMD); Alzheimer's disease; Atherosclerosis and C3 glomerulopathy ( Meri S and Haapasalo K (2020)"Function and Dysfunction of Complement Factor H During Formation of Lipid-Rich Deposits. Front. Immunol. 11:611830. doi: 10.3389 /fimmu.2020.611830)
Method: One solution to aging problem is to strengthen the physiological working of alternate complement system by inhibiting its dysfunction.
Results: Sulfonic nano polymers in right dose and formulation strategy can be used for inhibition of alternate complement system dysfunction and can increase its potential for the therapy for aging as well as prophylaxis for age related illnesses.