Tatiana Khimich – As. of prof., Department of Propaedeutic of internal diseases №2 and nursing, Kharkiv National Medical University; Olena Pionova – As. of prof., Department of Propaedeutic of internal diseases №2 and nursing, Kharkiv National Medical University
Abstract Text: The management of pregnancy and childbirth in women with hereditary angioedema (HAE) has important practical implications. We present a clinical case – patient A., 26 years old. The diagnosis of HAE was established at the age of 25 years. The disease made its debut at the age of 10 years. The patient became pregnant one year after the diagnosis was made. During pregnancy noted frequent attacks of angioedema. The most severe course of HAE was in the second trimester, when attacks occurred every 3 days and were manifested by swelling of the hands, forearms, abdominal and lumbar areas, buttocks, thighs and feet, which caused severe physical discomfort. The doctor found during the interview that the patient did not comply with the prescribed treatment regimen, which probably caused the worsening of the disease during pregnancy. Doctor recommended compliance with the pre-assigned regimen of drug administration - 1000 IU every 3 days. Physicians were of great concern regarding the choice of method of delivery for a pregnant woman with HAE. As a result, a healthy child was born by caesarean section. In this case, in addition to the long path to the diagnosis, we have the problem of compliance by patients with the frequency of prophylactic administration of the drug for the treatment of HAE. It is important to focus attention on this problem with conversation with the patient, because only the introduction of an adequate amount of the drug can give the expected therapeutic effect.
