Assistant Professor
Brigham and Women's Hospital
Needham, Massachusetts, United States
Dr. Guerriero is an Assistant Professor at Harvard Medical School and her laboratory is in the Division of Breast Surgery, Department of Surgery, at Brigham and Women's Hospital (BWH). Dr. Guerriero also serves at the Director of the Breast Tumor Immunology Laboratory at Dana-Farber Cancer Institute (DFCI). The Guerriero Lab aims to design clinically effective strategies to promote T-cell activation and weaken the immune-suppressive tumor microenvironment to improve immunotherapy response rates in breast cancer patients. They seek to identify tumor-promoting tumor macrophages in breast tumors before and after therapy, elucidate their molecular and metabolic regulation that promotes immune suppression and therapy-resistance and determine how tumor macrophage phenotype, metabolism and function can be modulated for anti-tumor responses.
Dr. Guerriero received her bachelor’s degree in BioChemistry from Northeastern University and has a PhD in Molecular and Cellular Biology and Immunology and Pathology from Stony Brook University. She completed her postdoctoral training in the laboratory of Dr. Anthony Letai at DFCI where she investigated the role of tumor associated macrophages in breast cancer and identified novel mechanisms to target pro-tumor macrophages to an anti-tumor phenotype to induce tumor regression. Dr. Guerriero transitioned to a faculty position as an Instructor in Medicine at Harvard Medical School and joined Dr. Mittendorf's laboratory as the Director of the Breast Tumor Immunology Laboratory at DFCI. In October 2020 Dr. Guerriero launched her independent laboratory at BWH and continues to serve as the Director of the Breast Tumor Immunology Laboratory at DFCI.
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Cancer Immunity & Immunotherapy Course
Tuesday, June 20, 2023
7:30 AM – 5:45 PM
